Publications
Peer-Reviewed Publications
- Eric G.B. Evans, Glenn L. Millhauser. Acta Pharmaceutica Sinica 2015; 563:503-27. doi: 10.1016/bs.mie.2015.06.008. Epub 2015 Jul 2
- Xu, Ze-Qi; Xu, Z.-Y. Recent Progress in Development of Antibiotics against Gram-Negative Bacteria. Acta Pharmaceutica Sinica 2013; 48(7): 993–1004. See details
- Gelhaus, H.C.; Anderson, M.S.; Fisher, D.A.; Flavin, M.T.; Xu, Ze-Qi; Sanford, DC. Efficacy of Post Exposure Administration of Doxycycline in a Murine Model of Inhalational Melioidosis. Sci Rep 2013; 3:1146. doi: 10.1038/srep01146.
- R. James Christie, Ryan Fleming, Binyam Bezabeh, Rob Woods, Shenlan Mao, Jay Harper, Augustine Joseph, Qianli Wang, Ze-Qi Xu, Herren Wu, Changshou Gao, Nazzareno Dimasi, “Stabilization of cysteine-linked antibody drug conjugates with N-aryl maleimides”, Journal of Controlled Release, 220, 660–670 2015, Link
- Stelios Florinas, Marc Liu, Ryan Fleming, Lilian Van Vlerken-Ysla, Joanne Ayriss, Ryan Gilbreth, Nazzareno Dimasi, Changshou Gao, Herren Wu, Ze-Qi Xu, Shaoyi Chen, Anjaneyulu Dirisala, Kazunori Kataoka, Horacio Cabral, R. James Christie, “A Nanoparticle Platform To Evaluate Bioconjugation and Receptor-Mediated Cell Uptake Using Cross-Linked Polyion Complex Micelles Bearing Antibody Fragments”, Biomacromolecules, 17, 1818−1833 2016, DOI: Link
- Shaoyi Chena, Stelios Florinas, Abigail Teitgen, Ze-Qi Xu, Changshou Gao, Herren Wu, Kazunori Kataokad, Horacio Cabral and R. James Christie, “Controlled Fab installation onto polymeric micelle nanoparticles for tuned Bioactivity”, Science and Technology of Advanced Materials, 18 (1), 666–680 2017, Link
- Wuping Ma, Richard S. Ma, Daniel Z. Fang, 45 th National Organic Symposium in Davis, CA, June 25-29, Poster No. T27, “PhI-Catalyzed α-osyloxylation of Cyclopropyl methyl ketone”.
- Wuping Ma, Alexander J. Ma, Daniel Z. Fang, 252nd ACS National Meeting in Philadelphia, PA, August 21-25, Poster ORG528, “Bromoethylation of Phenols”.
Referenced in Peer-Reviewed Publications
- Samadikhah, H.R.; Majidi, A.; Nikkhah, M.; Hosseinkhani, S. Preparation, Characterization, and Efficient Transfection of Cationic Liposomes and Nanomagnetic Cationic Liposomes. Int J Nanomedicine. 2011; 6:2275–2283. doi: 10.2147/IJN.S23074
- Li, F.; Lu, J.; Wang, L.; Ma, X. CYP3A-Mediated Generation of Aldehyde and Hydrazine in Atazanavir Metabolism. Drug Metab. Dispos. 2011; 39(3):394–401. doi: 10.1124/dmd.110.036327
- Wallace, J.L.; Caliendo, G.; Santagada, V .; Cirino, G. Markedly Reduced Toxicity of a Hydrogen Sulphide-Releasing Derivative of Naproxen (ATB-346). Br. J. Pharmacol. 2010; 159(6): 1236–1246 link
- Karaman, M.W.; Herrgard, S.; Treiber, D.K.; Gallant, P.; Atteridge, C.E.; Campbell, B.T.; Chan, K.W.; Ciceri, P.; Davis, M.I.; Edeen, P.T.; Faraoni, R.; Floyd, M.; Hunt, J.P.; Lockhart, D.J.; Milanov, Z.V.; Morrison, M.J.; Pallares, G.; Patel, H.K; Pritchard. S.; Wodicka, L.M.; Zarrinkar, P.P. A Quantitative Analysis of Kinase Inhibitor Selectivity. Nat Biotechnol. 2008; 26(1):127-132. link
- McClay, K.; Boss, C.; Keresztes, I.; Steffan, R.J. Mutations of Toluene-4-Monooxygenase That Alter Regiospecificity of Indole Oxidation and Lead to Production of Novel Indigoid Pigments. Appl. Environ. Microbiol. 2005; 71(9): 5476–5483.doi: 10.1128/AEM.71.9.5476-5483.2005
- Sprandel, K.A.; Schriever, C.A.; Pendland, S.L.; Quinn, J.P.; Gotfried, M.H.; Hackett, S.; Graham, M.B.; Danziger, L.H.; Rodvold, K.A. Pharmacokinetics and Pharmacodynamics of Intravenous Levofloxacin at 750 Milligrams and Various Doses of Metronidazole in Healthy Adult Subjects. Antimicrob. Agents Chemother. 2004; 48(12): 5476–548: 4597–46053.doi: 10.1128/AAC.48.12.4597-4605.2004
- Ying Zhou, Tomohiko Fukuda, Qinglei Hang, Sicong Hou, Tomoya Isaji, Akihiko Kameyama, Jianguo Gu, Nature, Scientific Report, 7, 11563 2017, “Inhibition of fucosylation by 2-fluorofucose suppresses human liver cancer HepG2 cell proliferation and migration as well as tumor formation”, the paper can be found here
Co-Authored in US Patent
- Lockwood, S.F.; Tang, P.C.; Nadolski, G.; Jackson, H.L.; Fang, Z.; Du, Y.; Yang, M.; Geiss, W.; Williams, R.; Burdick, D. Methods for synthesis of carotenoids, including analogs, derivatives, and synthetic and biological intermediates. US Patent 7,435,861. October 14, 2008. (Cardax Pharmaceuticals, Inc.)
- Lockwood, S.F.; Tang, P.C.; Nadolski, G.; Jackson, H.L.; Fang, Z.; Du, Y.; Yang, M.; Geiss, W.; Williams, R.; Burdick, D. Methods for the synthesis of astaxanthin. US Patent 7,247,752. July 24, 2007. (Cardax Pharmaceuticals, Inc.)
- Ze-Qi Xu, Qianli Wang, Augustine Rudolph Joseph, Zhiqiang Fang, THIOL- ENE CLICK CHEMISTRY FOR DRUG CONUGATES, US Patent, 9,056,141 B2, June 16, 2015.
Referenced in US Patents
- Balan, C.; Chen, N.; Doherty, E.M.; Gore, V.K.; Norman, M.H. ; Wang, H.-L. Vanilloid receptor ligands and their use in treatments. US Patent 8,227,469, July 24, 2012. (Amgen Inc.)
- Erickson, S.D.; Gillespie, P.; Guertin, K.R.; Karnachi, P.S.; Kim, K.; Ma, C.; McComas, W.W.; Pietranico-Cole, S.L.; Qi, L.; Tilley, J.W.; Zhang, Q. GPR119 receptor agonists. US Patent 8,188,098, May 29, 2012. (Hoffmann-La Roche Inc.)
- Heidelbaugh, T.M.; Chow, K.; Nguyen, P.X.; Gil, D.W.; Donello, J.E.; Garst, M.; Wheeler L.A.; Cappiello, J.R. Unsubstituted and substituted 4-benzyl-1,3-dihydro-imidazole-2-thiones acting as specific or selective alpha.sub.2 adrenergic agonists and methods for using the same. US Patent 8,178,571. May 15, 2012. (Allergan, Inc.)
- Roth, M.; Fontoura, B.; Wei, S.; Satterly, N. Inhibitors of the influenza virus non-structural 1 protein. US Patent 8,119,656. February 21, 2012. (University of Texas)
- Posner, G.H. ; Lee, J.K.; Wang, Q.; Crawford, K.R.; Yang, H.W.; Silverman, S.M.; Suh, B.-C.; White, J.A. ; Jones, G.; Saha U.; Jeon, H. B. 25-SO2-substituted analogs of 1µ,25-dihydroxyvitamin D3. US Patent 8,119,656. February 21, 2012. (University of Texas)
- Merla, B.; Kuehnert, S.; Frank, R.; Kaulartz, D.; Schroeder, W.; Bahrenberg, G.; Schiene, K.; Substituted nicotinamide compounds and uses thereof. US Patent 8,084,470. December 27, 2011. (Gruenenthal GmbH)
- Lockwood, S.F.; Mason, R.P. Carotenoid analogs and derivatives for the prevention of platelet aggregation. US Patent 8,063,101. November 22, 2011. (Cardax Pharmaceuticals, Inc.)
- Boettcher, A.; Buschmann, N.; Furet, P.; Groell, J.-M.; Kallen, J.; Hergovich Lisztwan, J.; Masuya, K.; Mayr, L.; Vaupel, A. 3-imidazolyl-indoles for the treatment of proliferative diseases. US Patent8,053,457. November 8, 2011. (Novartis AG)
- Wacker, D.A.; Rossi, K.A.; Wang, Y. Pyridone GPR119 G protein-coupled receptor agonists. US Patent 8,003,796. August 23, 2011. (Bristol-Myers Squibb Company)
- Hebeisen, P. ; Kitas, E.A.; Minder, R.E.; Mohr, P.; Wessel, H.P. Aminothiazoles as FBPase inhibitors for diabetes. US Patent 7,973,051. July 5, 2011. (Hoffman-La Roche Inc.)
- Bartolini, W.; Cali, B.M.; Chen, B.; Chien, Y.-T.; Currie, M.G.; Milne, G.T.; Pearson, J.P.; Talley, J.J.; Yang, J.; Zimmerman, C.; Kim, C.; Sprott, K.; Barden, T.; Lundigran, R.; Mermerian, A. Useful indole compounds. US Patent 7,960,544. June 14, 2011. (Ironwood Pharmaceuticals, Inc.)
- Cui, J.J.; Funk, L.A.; Jia, L.; Kung, P.-P.; Meng, J.J.; Nambu, M.D.; Pairish, M.A.; Shen, H.; Tran-Dube, M. Enantiomerically pure aminoheteroaryl compounds as protein kinase inhibitors. US Patent 7,858,643. December 28, 2010. (Agouron Pharmaceuticals, Inc.)
- Heidelbaugh, T.M.; Chow, K.; Nguyen, P.X.; Gill, D.W.; Donello, J.E.; Garst, M.E.; Wheeler, L.A. 4-(Condensed cyclicmethyl)-imidazole-2-thiones acting as a2 adrenergic agonists. US Patent 7,838,545. November 23, 2010. (Allergan, Inc)
- Hobson, A.D.; Fix-Stenzel, S.R.; Cusack, K.P.; Breinlinger, E.C.; Ansell, G.K.; Stoffel, R.H.; Woller, K.R.; Grongsaard, P. Oxadiazole compounds. US Patent 7,834,039. November 16, 2010. (Abbott Laboratories)
- Heidelbaugh, T.M.; Chow, K.; Nguyen, P.X.; Gill, D.W.; Donello, J.E.; Garst, M.E.; Wheeler, L.A.; Cappiello, J.R. Unsubstituted and substituted 4-benzyl-1,3-dihydro-imidazole-2-thiones acting as specific or selective alpha2 adrenergic agonists and methods for using the same. US Patent 7,795,292. September 14, 2010. (Allergan, Inc)
- Sams, A.G.; Bang-Andersen, B.; Mikkelsen, G.; Larsen, M. Pro-drugs of N-thiazol-2-yl-benzamide derivatives. US Patent 7,674,912. March 9, 2010. (H. Lundbeck A/S)
- Balan, C.; Chen, N.; Doherty, E.M.; Gore, V.K.; Norman, M.H.; Wang, H.-L. Vanilloid receptor ligands and their use in treatments. US Patent 7,534,798. May 19, 2009. (Amgen Inc.)
- Gillespie, P.; Goodnow, R.A., Jr.; Tilley, J.W. Biaryloxymethylarenecarboxylic acids as glycogen synthase activators. US Patent 7,524,870. April 28, 2009. (Hoffmann-La Roche Inc.)
- Wang, H.-L.; Balan, C.; Doherty, E.M.; Falsey, J.R.; Gore, V.K.; Katon, J.; Norman, M.H. Vanilloid receptor ligands and their use in treatments. US Patent 7,511,044. March 31, 2009. (Amgen Inc.)
- Norman, M.H.; Ognyanov, V.I.; Wang, X. Benzo[d]imidazol analogs as vanilloid receptor ligands and their use in treatments. US Patent 7,429,608. September 30, 2008. (Amgen Inc.)
- Heidelbaugh, T.M.; Chow, K.; Nguyen, P.X.; Gill, D.W.; Donello, J.E.; Garst, M.E.; Wheeler, L.A. 4-(Condensed cyclicmethyl)-imidazole-2-thiones acting as a2 adrenergic agonists. US Patent 7,396,849. July 8, 2008. (Allergan, Inc)
- Chen, N.; Nixey, T.; Norman, M.H. Vanilloid receptor ligands and their use in treatments. US Patent 7,390,907. June 24, 2008. (Amgen Inc.)
- Hui, R.A.; Root, R.T. Methods of inhibiting transmission of a costimulatory signal of lymphocytes. US Patent 7,157,561. January 2, 2007. (Roche Diagnostics Operations, Inc.)