Torin1 is a potent and selective mTOR inhibitor (IC50 = 2 - 10 nM for mTORC1 and mTORC2). Displays 200-fold selectivity for mTOR over DNA-PK, ATM and hVps34.
QuantityPrice
10 mg
195.00
50 mg
825.00
C35H28F3N5O2
1222998-36-8
98+%
MFCD18782653
BAM66470GSK-2126458
GSK2126458 is a highly potent PI3K and mTOR inhibitor with an app Ki of 19 pM for PI3K.
PP121 is a multitargeted dual receptor tyrosine kinases inhibitor with IC50 of 0.052, 1.4, 0.15, 1.1, 0.06, 0.01and 0.002 µM for p110a, p110ß, p110d, p110?, DNA-PK, mTOR and PDGFR, respectively.