Publications

Peer-Reviewed Publications

  • Eric G.B. Evans, Glenn L. Millhauser. Acta Pharmaceutica Sinica 2015; 563:503-27. doi: 10.1016/bs.mie.2015.06.008. Epub 2015 Jul 2
  • Xu, Ze-Qi; Xu, Z.-Y. Recent Progress in Development of Antibiotics against Gram-Negative Bacteria. Acta Pharmaceutica Sinica 2013; 48(7): 993–1004. See details
  • Gelhaus, H.C.; Anderson, M.S.; Fisher, D.A.; Flavin, M.T.; Xu, Ze-Qi; Sanford, DC. Efficacy of Post Exposure Administration of Doxycycline in a Murine Model of Inhalational Melioidosis. Sci Rep 2013; 3:1146. doi: 10.1038/srep01146.

Referenced in Peer-Reviewed Publications

  • Samadikhah, H.R.; Majidi, A.; Nikkhah, M.; Hosseinkhani, S. Preparation, Characterization, and Efficient Transfection of Cationic Liposomes and Nanomagnetic Cationic Liposomes. Int J Nanomedicine. 2011; 6:2275–2283. doi: 10.2147/IJN.S23074
  • Li, F.; Lu, J.; Wang, L.; Ma, X. CYP3A-Mediated Generation of Aldehyde and Hydrazine in Atazanavir Metabolism. Drug Metab. Dispos. 2011; 39(3):394–401. doi: 10.1124/dmd.110.036327
  • Wallace, J.L.; Caliendo, G.; Santagada, V .; Cirino, G. Markedly Reduced Toxicity of a Hydrogen Sulphide-Releasing Derivative of Naproxen (ATB-346). Br. J. Pharmacol. 2010; 159(6): 1236–1246 link
  • Karaman, M.W.; Herrgard, S.; Treiber, D.K.; Gallant, P.; Atteridge, C.E.; Campbell, B.T.; Chan, K.W.; Ciceri, P.; Davis, M.I.; Edeen, P.T.; Faraoni, R.; Floyd, M.; Hunt, J.P.; Lockhart, D.J.; Milanov, Z.V.; Morrison, M.J.; Pallares, G.; Patel, H.K; Pritchard. S.; Wodicka, L.M.; Zarrinkar, P.P. A Quantitative Analysis of Kinase Inhibitor Selectivity. Nat Biotechnol. 2008; 26(1):127-132. link
  • McClay, K.; Boss, C.; Keresztes, I.; Steffan, R.J. Mutations of Toluene-4-Monooxygenase That Alter Regiospecificity of Indole Oxidation and Lead to Production of Novel Indigoid Pigments. Appl. Environ. Microbiol. 2005; 71(9): 5476–5483.doi: 10.1128/AEM.71.9.5476-5483.2005
  • Sprandel, K.A.; Schriever, C.A.; Pendland, S.L.; Quinn, J.P.; Gotfried, M.H.; Hackett, S.; Graham, M.B.; Danziger, L.H.; Rodvold, K.A. Pharmacokinetics and Pharmacodynamics of Intravenous Levofloxacin at 750 Milligrams and Various Doses of Metronidazole in Healthy Adult Subjects. Antimicrob. Agents Chemother. 2004; 48(12): 5476–548: 4597–46053.doi: 10.1128/AAC.48.12.4597-4605.2004

Co-Authored in US Patent

  • Lockwood, S.F.; Tang, P.C.; Nadolski, G.; Jackson, H.L.; Fang, Z.; Du, Y.; Yang, M.; Geiss, W.; Williams, R.; Burdick, D. Methods for synthesis of carotenoids, including analogs, derivatives, and synthetic and biological intermediates. US Patent 7,435,861. October 14, 2008. (Cardax Pharmaceuticals, Inc.)
  • Lockwood, S.F.; Tang, P.C.; Nadolski, G.; Jackson, H.L.; Fang, Z.; Du, Y.; Yang, M.; Geiss, W.; Williams, R.; Burdick, D. Methods for the synthesis of astaxanthin. US Patent 7,247,752. July 24, 2007. (Cardax Pharmaceuticals, Inc.)

Referenced in US Patents

  • Balan, C.; Chen, N.; Doherty, E.M.; Gore, V.K.; Norman, M.H. ; Wang, H.-L. Vanilloid receptor ligands and their use in treatments. US Patent 8,227,469, July 24, 2012. (Amgen Inc.)
  • Erickson, S.D.; Gillespie, P.; Guertin, K.R.; Karnachi, P.S.; Kim, K.; Ma, C.; McComas, W.W.; Pietranico-Cole, S.L.; Qi, L.; Tilley, J.W.; Zhang, Q. GPR119 receptor agonists. US Patent 8,188,098, May 29, 2012. (Hoffmann-La Roche Inc.)
  • Heidelbaugh, T.M.; Chow, K.; Nguyen, P.X.; Gil, D.W.; Donello, J.E.; Garst, M.; Wheeler L.A.; Cappiello, J.R. Unsubstituted and substituted 4-benzyl-1,3-dihydro-imidazole-2-thiones acting as specific or selective alpha.sub.2 adrenergic agonists and methods for using the same. US Patent 8,178,571. May 15, 2012. (Allergan, Inc.)
  • Roth, M.; Fontoura, B.; Wei, S.; Satterly, N. Inhibitors of the influenza virus non-structural 1 protein. US Patent 8,119,656. February 21, 2012. (University of Texas)
  • Posner, G.H. ; Lee, J.K.; Wang, Q.; Crawford, K.R.; Yang, H.W.; Silverman, S.M.; Suh, B.-C.; White, J.A. ; Jones, G.; Saha U.; Jeon, H. B. 25-SO2-substituted analogs of 1µ,25-dihydroxyvitamin D3. US Patent 8,119,656. February 21, 2012. (University of Texas)
  • Merla, B.; Kuehnert, S.; Frank, R.; Kaulartz, D.; Schroeder, W.; Bahrenberg, G.; Schiene, K.; Substituted nicotinamide compounds and uses thereof. US Patent 8,084,470. December 27, 2011. (Gruenenthal GmbH)
  • Lockwood, S.F.; Mason, R.P. Carotenoid analogs and derivatives for the prevention of platelet aggregation. US Patent 8,063,101. November 22, 2011. (Cardax Pharmaceuticals, Inc.)
  • Boettcher, A.; Buschmann, N.; Furet, P.; Groell, J.-M.; Kallen, J.; Hergovich Lisztwan, J.; Masuya, K.; Mayr, L.; Vaupel, A. 3-imidazolyl-indoles for the treatment of proliferative diseases. US Patent8,053,457. November 8, 2011. (Novartis AG)
  • Wacker, D.A.; Rossi, K.A.; Wang, Y. Pyridone GPR119 G protein-coupled receptor agonists. US Patent 8,003,796. August 23, 2011. (Bristol-Myers Squibb Company)
  • Hebeisen, P. ; Kitas, E.A.; Minder, R.E.; Mohr, P.; Wessel, H.P. Aminothiazoles as FBPase inhibitors for diabetes. US Patent 7,973,051. July 5, 2011. (Hoffman-La Roche Inc.)
  • Bartolini, W.; Cali, B.M.; Chen, B.; Chien, Y.-T.; Currie, M.G.; Milne, G.T.; Pearson, J.P.; Talley, J.J.; Yang, J.; Zimmerman, C.; Kim, C.; Sprott, K.; Barden, T.; Lundigran, R.; Mermerian, A. Useful indole compounds. US Patent 7,960,544. June 14, 2011. (Ironwood Pharmaceuticals, Inc.)
  • Cui, J.J.; Funk, L.A.; Jia, L.; Kung, P.-P.; Meng, J.J.; Nambu, M.D.; Pairish, M.A.; Shen, H.; Tran-Dube, M. Enantiomerically pure aminoheteroaryl compounds as protein kinase inhibitors. US Patent 7,858,643. December 28, 2010. (Agouron Pharmaceuticals, Inc.)
  • Heidelbaugh, T.M.; Chow, K.; Nguyen, P.X.; Gill, D.W.; Donello, J.E.; Garst, M.E.; Wheeler, L.A. 4-(Condensed cyclicmethyl)-imidazole-2-thiones acting as a2 adrenergic agonists. US Patent 7,838,545. November 23, 2010. (Allergan, Inc)
  • Hobson, A.D.; Fix-Stenzel, S.R.; Cusack, K.P.; Breinlinger, E.C.; Ansell, G.K.; Stoffel, R.H.; Woller, K.R.; Grongsaard, P. Oxadiazole compounds. US Patent 7,834,039. November 16, 2010. (Abbott Laboratories)
  • Heidelbaugh, T.M.; Chow, K.; Nguyen, P.X.; Gill, D.W.; Donello, J.E.; Garst, M.E.; Wheeler, L.A.; Cappiello, J.R. Unsubstituted and substituted 4-benzyl-1,3-dihydro-imidazole-2-thiones acting as specific or selective alpha2 adrenergic agonists and methods for using the same. US Patent 7,795,292. September 14, 2010. (Allergan, Inc)
  • Sams, A.G.; Bang-Andersen, B.; Mikkelsen, G.; Larsen, M. Pro-drugs of N-thiazol-2-yl-benzamide derivatives. US Patent 7,674,912. March 9, 2010. (H. Lundbeck A/S)
  • Balan, C.; Chen, N.; Doherty, E.M.; Gore, V.K.; Norman, M.H.; Wang, H.-L. Vanilloid receptor ligands and their use in treatments. US Patent 7,534,798. May 19, 2009. (Amgen Inc.)
  • Gillespie, P.; Goodnow, R.A., Jr.; Tilley, J.W. Biaryloxymethylarenecarboxylic acids as glycogen synthase activators. US Patent 7,524,870. April 28, 2009. (Hoffmann-La Roche Inc.)
  • Wang, H.-L.; Balan, C.; Doherty, E.M.; Falsey, J.R.; Gore, V.K.; Katon, J.; Norman, M.H. Vanilloid receptor ligands and their use in treatments. US Patent 7,511,044. March 31, 2009. (Amgen Inc.)
  • Norman, M.H.; Ognyanov, V.I.; Wang, X. Benzo[d]imidazol analogs as vanilloid receptor ligands and their use in treatments. US Patent 7,429,608. September 30, 2008. (Amgen Inc.)
  • Heidelbaugh, T.M.; Chow, K.; Nguyen, P.X.; Gill, D.W.; Donello, J.E.; Garst, M.E.; Wheeler, L.A. 4-(Condensed cyclicmethyl)-imidazole-2-thiones acting as a2 adrenergic agonists. US Patent 7,396,849. July 8, 2008. (Allergan, Inc)
  • Chen, N.; Nixey, T.; Norman, M.H. Vanilloid receptor ligands and their use in treatments. US Patent 7,390,907. June 24, 2008. (Amgen Inc.)
  • Hui, R.A.; Root, R.T. Methods of inhibiting transmission of a costimulatory signal of lymphocytes. US Patent 7,157,561. January 2, 2007. (Roche Diagnostics Operations, Inc.)